Conferences Widya Mandala Surabaya Catholic University, International Food Conference 2021

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Efficacy of Soy Biopeptide Amongst Adolescents in Pandeglang Districts in Indonesia
noer laily, galih kusuma aji, iim sukarti, ida susanti, fatim illaningtyas, hardaning pranamuda

Last modified: 2021-09-06


Objective: The study aimed to analyse the efficacy of a biopeptide hydrolisate in improving the serum iron, serum ferritin and hemoglobin among female adolescents. The biopeptide hydrolisate product is made from soybean and enriched with multi micronutrients including iron after two weeks of consumption. Design: For the product’s efficacy study we conducted a one group pretest – posttest design. The biopeptide was given everyday for 14 days. The serum iron, serum ferritin and hemoglobin were measured twice at prior to administration and after day 14. The efficacy study was conducted in Pandeglang district, BantenParticipants: The respondents for the efficacy study were 52 respondents of female adolescent girls who met the inclusion criteria and had completed the trial until day 14.  

Results: The serum iron was significantly improved after the biopeptide administration from 66.87± 32.44 to 103.77 ± 55.87 (p=0.000). While on the other hand serum ferritin was significantly improved with the biopedtides administration in respondents with low level of serum ferritin from 13,29 ± 9,5 to 17,48 ± 12,18 (p=0,00) but showed no difference in the group with normal serum ferritin from 28,06 ± 23,7 to 29,05 ± 21,3 (p=0,64). The average haemoglobin level of the resepondent before the biopeptide administration was normal 12.21 ± 1.29  and it did not change significantly after the biopeptide administration (12.05  ± 1.31 (0.016)). Hemoglobin did not increase significantly, probably because the hemoglobin was at a normal level

Conclusions: Soy Peptide products have the health benefits of increasing serum iron and serum ferritin.Keywords: soy-biopeptides, serum iron, serum ferritin, haemoglobin


Public health


Angeles-Agdeppa I, Schultink W, Sastroamidjojo S et al. (1997) Weekly micronutrient supplementation to build iron stores in female Indonesian adolescents. The American journal of clinical nutrition 66, 177-183

Briawan D KA, Ekayanti I, Dewi M. . (2018) Baseline survey for an improved IFA supplementation program for 15 to 19 years of age school going adolescent girls (mitra youth) in East Java and East Nusa Tenggara province in Indonesia. Jakarta.

Jayatissa R & Piyasena C (1999) Adolescent schoolgirls: Daily or weekly iron supplementation? Food and Nutrition Bulletin 20, 429-434

Kassebaum NJ, Jasrasaria R, Naghavi M et al. (2014) A systematic analysis of global anemia burden from 1990 to 2010. Blood 123, 615-624.

MoH (2013) Riset kesehatan dasar (Riskesdas) 2013. Jakarta: Badan Penelitian dan Pengembangan Kesehatan.

MoH (2016) Pemberian tablet tambah darah pada remaja putri dan wanita usia subur. Indonesia.

Organization WH (2014) Global nutrifion targets 2025: anaemia policy brief. Global Nutrition Targets 2025.

Universitas Indonesia Mi (2016) Formative reasearch for an improved iron folic acid suplementation program for school going adolescent in selected of West Java province in Indonesia.

Vasanthi G, Fawashe A, Susie H et al. (1994) Iron nutritional status of adolescent girls from rural area and urban slum. Hemoglobin (g/dl) 12, 13.10-11.92.